Simplicef for dogs with a bacterial infection

(redirects here from cefpodoxime)

This article provides information about the use of cefpodoxime (Simplicef) for dogs including dosage, safety guidelines, side effects and more.

Simplicef, the popular brand name for the veterinary formulation of cefpodoxime, is an antibiotic medication detailed for use in dogs. The medicine is cephalosporin based which means that it is safe to use in patients with an allergy to penicillin[1] to fight bacterial infections. Like most other cephalosporin based antibiotics, Simplicef works by suppressing the growth of micro-organisms such as bacteria, but can also suppress growth of fungi and protozoa. It is illegal to administer this drug to your dog without veterinary instruction to do so.

Simplicef dosage for dogs

Typical dosage of Simplicef (cefpodoxime) in dogs is 2.3 to 4.5 mg/lb body weight to be administered once a day (every 24 hours). The agreed dosage will depend on several factors such as the severity of your dog’s infection and the micro-organism’s resistance to the drug. Typically, a sample of the pathogen may be taken for a sensitivity test prior to prescription. Tests may also be done to rule out the possibility that your dog’s symptoms are being caused by a virus, against which all antibiotics including Simplicef are uneffective. It is safe to give this drug both with and without food. The drug is available as 100 mg or 200 mg pills, and as an oral suspension. When using oral suspension take note of the concentration when working out the amount to give, as the target mg/lb is the same.

As with all antibiotics, it’s important that you complete the entire course of treatment. Ceasing to administer the antibiotic as soon as symptoms begin to subside could lead to the infection coming back.

Is Simplicef safe for dogs?

Lysodren is mostly safe for use in dogs. There is a slight risk of allergic reaction if your dog has a known penicillin allergy but this only occurs in roughly 1% of patients. To keep yourself protected against possible allergic reactions if you are sensitive to antibiotics avoid direct contact of the medicine with your skin.

Safety precautions

  • Do not give this medicine to your dog without a prescription
  • Notify your vet if your dog suffers with renal disease or has a history of seizures
  • Be on the lookout for possible signs of allergic reaction
  • Do not administer this medicine alongside antacids
  • Do not give to dogs with known allergies to cephalosporin

Allergic reactions when giving Simplicef to dogs with a penicillin allergy is rare, but still possible. Signs of an allergic reaction includes swelling, fainting, shortness of breath, rashes, hives, vomiting, blood in stools and unusual bleeding/bruising. If your dog displays signs of an allergic reaction stop administering the drug immediately and seek emergency veterinary attention. Always get a prescription before using Simplicef.

Uses of Simplicef for dogs

Simplicef is a drug most commonly prescribed by vets for the treatment of:

Side effects of giving Simplicef to your dog

As mentioned earlier, the main concern when giving your dog Simplicef is the possibility of allergic reaction. Seek veterinary attention immediately and stop giving the medicine to your pet if he/she displays signs such as difficulties breathing, swelling, rashes and hives. More common side effects include mild diarrhea, mild vomiting and yeast infection, you should notify your vet if you notice these signs or any others which appear to be bothersome to your pet.

Information about cefpodoxime
Cephalexin for dogs (cephalosporin based)

simplicef for dogs

[1] Study of cephalosporin allergy in patients with penicillin sensitivity.