Vetoryl (Trilostane) For Dogs Affected By Cushing’s Disease

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This article contains details about Vetoryl (trilostane) for dogs including the dosage, safety recommendations, side effects and other such information.

Trilostane (also commonly known as “Vetoryl) is a medication used commonly in the treatment of Cushing’s Disease in dogs. Trilostane works in dogs by inhibiting cortisol production in the adrenal gland. It is a prescription medication and requires you to visit the vet before use.

Trilostane dosage for dogs

The dosage of trilostane for dogs is size dependent. Pills come in various formulations ranging from 10 mg capsules up to 120 mg. Check the following table for typical dosage amounts:

Weight of dog Pills To Administer
3.8 – 10 lbs One 10 mg capsule
10.1 – 22 lbs One 30 mg capsule
22.1 – 44 lbs One 60 mg capsule
44.1 – 88 lbs One 120 mg capsule
88.1 – 132 lbs One 120 mg + one 60 mg capsule
> 132 lbs Speak to the vet

The dosage of trilostane for dogs typically lies between 1 to 3 mg/lb body weight administered once a day. Remember to always seek specific dosage recommendations from your vet and follow his or her instructions carefully. You will be required to go back to the vet on a regular basis for a check up and possible alteration of the dosage. Administer this medicine with food.

Is trilostane safe for dogs?

Trilostane is a relatively safe substance and should do no harm to your pet when given with veterinary approval and guidance. See below for safety guidelines.

Safety precautions

  • Never administer trilostane without a prescription and veterinary approval
  • Avoid use if your pet is pregnant, lactating or breeding
  • Notify the vet if your pet suffers from kidney or liver disease
  • Notify the vet of any other medicine, supplements or vitamins your pet is taking
  • Administer trilostane alongside food
  • Avoid direct contact with trilostane if you are pregnant or trying for a baby

Trilostane may interact with several other substances, so you should always tell your vet about other medicines or vitamins your pet is taking. Amongst these substances are ACE inhibitors such as benazepril. Vetoryl should be avoided in dogs who are pregnant, nursing or breeding, and pregnant pet owners should practice caution and avoid direct contact with the drug.

Uses of trilostane for dogs

Trilostane is a medication prescribed by vets for the treatment of:

  • Cushing’s disease

Side effects of trilostane use in dogs

Typical side effects include vomiting and diarrhea, fatigue and decreased appetite. If your pet suffers severe side effects such as an allergic reaction, fainting or blood in excrement you should seek emergency veterinary attention.

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